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TRPV1: The Paradoxical Pain Receptors of The Endocannabinoid System

TRPV1: The Paradoxical Pain Receptors of The Endocannabinoid System

by Adam Townsend | Dec 4, 2019 | Endocannabinoid System

One of the less-discussed parts of the endocannabinoid system is the point at which it dovetails with the subsystems that sense pain and burning and activate inflammation response — the TRP or “transient receptor potential” system of neuroreceptors. TRPV1 stands for...
MAGL (Monoacylglycerol Lipase): An Endocannabinoid Recylcing Enzyme

MAGL (Monoacylglycerol Lipase): An Endocannabinoid Recylcing Enzyme

by Adam Townsend | Dec 4, 2019 | Endocannabinoid System

Monoacylglycerol Lipase (MAGL) is the specialized enzyme that breaks down the endocannabinoid 2-AG, and it represents the point at which the endocannabinoid system dovetails with a system of signaling agents called eicosanoids. This is a schematic illustration of the...
2-AG (2-arachidonoylglycerol): The Endocannabinoid Of Balance

2-AG (2-arachidonoylglycerol): The Endocannabinoid Of Balance

by Adam Townsend | Dec 4, 2019 | Endocannabinoid System

If you survey the scientific literature on the endocannabinoid system, 2-AG (2-arachidonoylglycerol) seems like anandamide’s (AEA) neglected sibling. But 2-AG may be the more potent and important endocannabinoid.  It’s certainly the most ubiquitous; the typical...
CB2 receptors: Immune Support Within The Endocannabinoid System

CB2 receptors: Immune Support Within The Endocannabinoid System

by Adam Townsend | Nov 19, 2019 | Endocannabinoid System

CB2 receptors are the most mysterious of the components of the known endocannabinoid system, but figuring out exactly how they work could lead to revolutionary new treatments for autoimmune disease and other inflammatory disorders. The endocannabinoid system is the...
CB1 Receptors: The Endocannabinoid System’s Catcher’s Mitts For THC

CB1 Receptors: The Endocannabinoid System’s Catcher’s Mitts For THC

by Adam Townsend | Nov 13, 2019 | Endocannabinoid System

CB1, short for Cannabinoid Receptor 1, is the name of a molecule-sized docking station on the membranes of nerve cells throughout the brain, gut and to a lesser degree, the entire body. CB1 receptors are the most studied of the neuro-receptors that make up the...
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